Under the assumed name John Wiley, Reese is making his escape from his life with Finch and the Machine by taking a one-way flight to Istanbul. He is however diverted onto another flight via Rome. Initially believing it is all Finch’s doing, Reese soon learns that he was placed onto that Rome flight by the Machine, who provides him with the next number in the form of a seat number on the plane. „4C” is occupied by a young man named Owen Matthews, who is accompanied by who Reese recognizes as two federal marshals. Reese initially has no intention about doing anything …